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In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems

Macartney RADas AImaniyyah AGFricker ASmith AM, et al.

Journal of Tissue Engineering. 2025;16. doi:10.1177/20417314241313458

Safe and well-tolerated long-term parenteral nutrition regimen: Omega-3-fatty-acid-enriched medium chained/ long chained triglycerides emulsion.

Klek S, Chambrier C, Szczepanek K, et al.

Clinical Nutrition, 2024 Volume 43(12):415-424

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Randomized clinical trial: Long-term Staphylococcus aureus decolonization in patients on home parenteral nutrition

Gompelman M, Wezendonk GTJ, Wouters Y, Beurskens-Meijerink J et al.

Clinical Nutrition, 2023, 42 (5) pp. 706-716. 10.1016/j.clnu.2023.03.010.

The Role of Diet and Gut Microbiota in Regulating Gastrointestinal and Inflammatory Disease.

Gill PA, Inniss S, Kumagai T, Rahman FZ, Smith AM.

Front Immunol. 2022 Apr 5;13:866059. doi: 10.3389/fimmu.2022.866059. eCollection 2022.

Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line.

Mulvey CM, Breckels LM, Crook OM, Sanders DJ, Ribeiro ALR, Geladaki A, Christoforou A, Britovšek NK, Hurrell T, Deery MJ, Gatto L, Smith AM, Lilley KS.

Nat Commun. 2021 Oct 1;12(1):5773.

doi: 10.1038/s41467-021-26000-9.

A proof of concept pilot trial of probiotics in symptomatic oral lichen planus (CABRIO).

Marlina E, Goodman RN, Mercadante V, Shephard M, McMillan R, Hodgson T, Leeson R, Porter S, Barber JA, Fedele S, Smith AM.

Oral Dis. 2022 Nov;28(8):2155-2167. doi: 10.1111/odi.14014. Epub 2021 Sep 9.

Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.

Matei DE, Menon M, Alber DG, Smith AM, Nedjat-Shokouhi B, Fasano A, Magill L, Duhlin A, Bitoun S, Gleizes A, Hacein-Bey-Abina S, Manson JJ, Rosser EC; ABIRISK Consortium; Klein N, Blair PA, Mauri C.

Med (N Y). 2021 Jul 9;2(7):864-883.e9. doi: 10.1016/j.medj.2021.04.013.

The role of the microbiome in gastrointestinal inflammation.

Sanders DJ, Inniss S, Sebepos-Rogers G, Rahman FZ, Smith AM.

Biosci Rep. 2021 Jun 25;41(6):BSR20203850. doi: 10.1042/BSR20203850.

The Microbiome and Radiation Induced-Bowel Injury: Evidence for Potential Mechanistic Role in Disease Pathogenesis.

Kumagai T, Rahman F, Smith AM.

Nutrients. 2018 Oct 2;10(10):1405. doi: 10.3390/nu10101405.

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.

Smith AM, Rahman FZ, Hayee B, Graham SJ, Marks DJ, Sewell GW, Palmer CD, Wilde J, Foxwell BM, Gloger IS, Sweeting T, Marsh M, Walker AP, Bloom SL, Segal AW.

J Exp Med. 2009 Aug 31;206(9):1883-97. doi: 10.1084/jem.20091233. Epub 2009 Aug 3.

The LGLN is a forum for scientists, clinicians and other interested investigators to connect over their shared enthusiasm for gastroenterology and hepatology translational research. To find out more and joint the network click on the image.

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